Both Endnote and ChemDraw work on the M1 Mac but not natively. They run on the Rosetta 2 system. However, you won't notice much of a difference as these softwares run super fast on this M1 chip even when they don't run natively. There would only be one slight glitch as there is a new M1 compatible version of MS Word. EndNote for Mac. Your UGA Librarian trainers have not yet spent time with EndNote 20 in the Mac platform. However be aware of these areas of concern: i5-i7 AMD Intel chips versus new M1 chips: the newest Mac Books and Mac Airs run on new chips and there may be some settings and compatibility issues with Microsoft Products and other 3rd party.
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For your third party applications—You can query the developers website: FAQ, Help, Support or insight to known issues.
We do know that since the release of macOS 10.15 Catalina, all applications will have to be 64-bit. App developers will issue updated apps if they want their apps to work on this newest macOS upgrade
32-bit app compatibility with macOS... - Apple Support
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Mac computers with Apple silicon:
MacBook Pro (13-inch, M1, 2020)
MacBook Air (M1, 2020)
Mac mini (M1, 2020)
I can add—
Rosetta 2 an emulator built into macOS Big Sur that will enable ARM Macs (M1) to run old Intel applications. Rosetta 2 essentially “translates” instructions that were written for Intel processors into commands that Apple’s chips (SoC) can understand. Developers won’t need to make any changes to their old apps, they will just work.
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Rosetta 2 works with Intel-based apps distributed through the Mac App Store, and desktop applications downloaded and installed from external sources.
To the user, Rosetta is mostly transparent. If an executable contains only Intel instructions, macOS automatically launches Rosetta and begins the translation process.
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When launching any Mac apps for the first time on Apple Silicon Macs, the apps will bounce in the dock for approximately 20 seconds while the Rosetta 2 translation process is completed, with all subsequent launches being fast.
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Jan 3, 2021 9:48 PM
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